GS04 1223 Fundamental Mechanisms of Cancer Development
Gan, Boyi; Chen, Jichao. Three semester hours. Fall, annually. Grading System: Letter Grade. Prerequisite: None.
Cancer is defined by a series of abnormal events in the cell that lead to the formation of a tumor with the ability to spread to distant sites. Some hallmarks of cancer include aberrant proliferation, genomic instability, evasion of cell death and immune responses, and activation of a variety of cell growth signaling pathways. This course is organized into weekly modules consisting of 2 lectures and a journal club. Each module is organized to first describe each of these events as they occur during normal development or homeostasis followed by a lecture on how these processes or pathways go awry to develop cancer. The last lecture of each module consists of a journal club with class-wide discussions of a recent or classic paper in the field. Module topics will be fundamental, timely, and