Dr. Huamin Wang
The University of Texas MD Anderson Cancer Center
Department of Pathology, Anatomical
Pancreatic cancer is the fourth leading cause of cancer death for both men and women in the US. The molecular mechanisms leading to pancreatic cancer have not been elucidated. The goal of my research is to understand the role of oncogenes, tumor suppressor genes in the development of pancreatic cancer, and develop therapeutic targets for cancer treatments that are based on novel mechanisms of action. We are particularly interested in protein kinases and phosphatases that have been implicated in pancreatic cancer. Current research in my laboratory is directed to understand the function of the MAP4K family of mammalian Ste20-related protein kinases and their phosphatases in pancreatic cancer.
Depending on the student’s interests, a tutorial in my laboratory would provide experience with cell culture, animal models and surgical specimens from human pancreatic cancer. The student would learn basic molecular biology methods, participate in translational studies using antibody array, tissue microarray, siRNA, in vivo tumor models and gene delivery technology.