Dr. James P. Allison

Dr. James P.  Allison

Regular Member

Professor & Chair

The University of Texas MD Anderson Cancer Center
Department of Immunology

The general area of our research is the molecular immunology of the T cell antigen receptor complex, co-stimulatory receptors, and other molecules involved in T cell activation. We are particularly interested in defining those signaling events that lead to differentiation of naive T cells and those that determine whether antigen receptor engagement will lead to functional activation or inactivation of T cells. The lessons learned in these basic studies are used to develop new strategies for the treatment of autoimmune diseases and for immunotherapy of cancer.

Projects/Techniques:  Basic concepts of cancer immunology; Growth and characterization of tumor-reactive T-cells; Murine models of tumor immunotherapy; FACS analysis; ELISPOT and ELISA techniques

PubMed

Influuent

Contact Information

Phone: 713.563.3285 (assistant)

Email: jallison@mdanderson.org

Office: MDA SCR3.1035a (Unit 0901)

Education:

Ph.D. - The University of Texas at Austin - 1973

Programs: