Dr. Roza Nurieva
The University of Texas MD Anderson Cancer Center
Department of Immunology
Our research is to understand the molecular basis of T cell mediated immune responses, and how abnormal immune regulation leads to immunodeficiency, autoimmunity and cancer. These studies will help us to understand the function of the immune system, and will, therefore, help develop approaches to design drugs against cancer, as well as against autoimmune disorders.
A tutorial student would be involved in the research in the following projects: 1. The molecular mechanisms of T cell activation and tolerance; 2. The signaling and transcriptional mechanisms underlying T helper cell differentiation and function. This research direction will bridge the basic molecular biology and biochemistry to immune diseases and provide new ways of treating tumors.
A tutorial in this laboratory will provide training in molecular and cell biology techniques including molecular cloning, cell culture, mouse models, gene expression profiling, etc.