MD Anderson Cancer Center UTHealth
Graduate School of Biomedical Sciences

Dr. Hongyu Wang

Dr. Hongyu  Wang

Associate Member

Assistant Professor

The University of Texas Health Science Center at Houston
McGovern Medical School
Institute of Molecular Medicine

My research interests include

  • Biomarkers discovery and validation for cancer detection and prognosis. Combining aptamer technology with mass spectrometry proteomics, we can simultaneously discover high binding affinity aptamer sequences and aptamer associated target proteins as potential biomarkers for diagnostic, prognostic and imaging applications.
  • Applying a novel X-aptamer technology to cancer immunotherapy and biomarker discovery for clinical applications. We are going to develop a new platform to identify new generation X-aptamers that have high binding affinity to immune checkpoint inhibitors and immune modulators and can be used as an alternate to antibodies for predictive diagnosis and treatment of many types of cancers.
  • Linkages of genetic variations and protein biomarkers. Based on genetic analysis using Next-generation sequencing (NGS) and current proteomics/metabolomics studies, we will study the influences of regulatory genetic variation on biomarker status.

PubMed

Contact Information

Phone: 713.500.3404

Email: hongyu.wang@uth.tmc.edu

Office: SRB 330E

Education:

M.D. - Southeast University - China - 1986
Ph.D. - University of Kiel - Germany - 1997

Programs: