In addition to the general GSBS course requirements, the G&E Program requires the following courses:
*Any GSBS course(s) can be chosen for the elective -- work with the G&E program director, your research mentor and/or Advisory Committee to use this elective to customize your studies to support your educational objectives.
G&E Course Requirements for MD/PhD Students:
Students who declare a Secondary Area of Concentration in Genetics and Epigenetics are:
Elective Course Suggestions Taught By G&E Faculty
- Pragmatic Bioinformatics for Bench Scientists (1 credit)
- Advanced Topics in Epigenetics (1 credit)
- Practical Bioinformatics (1 credit)
- Advanced Topics in DNA Repair (1 credit)
- Introduction to Bioinformatics (3 credits)
- Critical Thinking in Science (1 credit)
- Developmental Biology (3 credits)
- Principles of Stem Cell Biology (2 credits)
Principles of Genetics and Epigenetics (required)
GS04 1253 (3 credits)
The Principles of Genetics and Epigenetics class is designed for students who have a major interest in aspects of epigenetics, experimental and human genetics. Students are required to have completed the core course and this class will provide in depth instruction on four areas: 1) Experimental genetics, 2) Human genetics, 3) Epigenetics, 4) Functional bioinformatics. Class will be held three times a week for one hour and students are expected to actively participate in the course by initiating discussions, asking questions and providing constructive comments. Students will be evaluated by attendance, participation and performance on a mid-term and final examination. This course is designed to prepare the student to generate novel hypothesis driven projects in the areas of genetics and epigenetics.
G&E Scientific Writing Course (required)
GS04 1811 (1 credit)
Fall 2020; Mondays 3-4pm
This course is designed for second year students who have already chosen the lab in which they will pursue their thesis research and have a thesis project. Students will be taught how to write scientific papers. One of the primary goals of graduate education is to teach students how to assess the primary literature and then synthesize that literature into understanding the field. It is from this understanding that new hypotheses are formulated and tested to move the research field forward. The goal of this class will be for each student to write a review of the literature in their field of research for submission and publication.
G&E Oral Scientific Presentations Course (required)
GS04 1821 (1 credit)
The G&E Scientific Presentation class is designed for second year students who have chosen their thesis lab and are preparing for their candidacy exam. The students will use their thesis project as a template to develop a 20-minute scientific presentation. All aspects of the presentation will be covered including title and introduction slides, organizing your data into a story, model slides and conclusions and answering questions. In addition to the 20-minute presentation students will also give two 90 second elevator talks one to a scientific group and one to a non-scientists group. Students will also present a 10 minute chalk talk based on the research plan that is based on the data from their 20-minute talk. This course is designed to prepare the student for the oral defense portion of their candidacy exam and to prepare the student to present their work in both short and long format platform presentations.
Pragmatic Bioinformatics for Bench Scientists
GS04 1781 (1 credit)
Bioinformatics is becoming essential in the genomic era. Witnessing both the power and the complexity of bioinformatics, bench scientists, despite providing most of the biological insights, often feel left out as simply data generators, and frustrated when collaborating with data analyzers. This course, taught by bench scientists who have published on specific bioinformatics topics, aims to empower bench scientists with valid statistical and computational methods to be able to explore data and communicate with computational scientists. It is pragmatic because it covers as-needed theoretical background and teaches usable, instead of efficient, programming in the format of a dry-lab protocol that generates publication-quality figures. It consists of 6 modules covering principles, RNA, DNA, protein, images, and freeware. Each module takes 4 hours of class time, which consists of one 30-minute background and three 1-hour sessions with significant hands-on time. Grades are based on homework.
Advanced Topics in Epigenetics
Fall 2020 (5 classes of three hours each, 1 credit)
This course is designed for students that have already chosen a laboratory and thesis project. Students are required to have completed the core course. This course will meet once a week for three hours during which students and faculty will discuss two important papers that focus on recent advances in the field of epigenetics. There will be no pre-prepared slides or specified presenters. Students will be evaluated by attendance and participation. This is a pass/fail class. By the end of this class, students will have a multifaceted and nuanced appreciation for the current state our knowledge of Epigenetics. This course will be video-conferenced between Smithville (Science Park) and Houston.
Advanced Topics in DNA Repair
Fall 2020 (5 classes of three hours each, 1 credit)
This course is designed for students that have already chosen a laboratory and thesis project. Students are required to have completed the core course. This course will meet once a week for three hours during which students and faculty will discuss two important papers on a specific problem of DNA repair per class in order to explore the hypotheses, logic, principles, and approaches that best exemplify the field. There will be no pre-prepared slides or specified presenters. Students will be evaluated by attendance and participation. This is a pass/fail class. By the end of this class, students will have a multifaceted and nuanced appreciation for the current state our knowledge of DNA repair.
GS04 1251 (1 credit)
Fall 2020 - 5 week course
The purpose of this course is to facilitate student learning, at an early stage of their research careers, regarding the basis and implementation of bioinformatics techniques that are especially applicable to research in modern molecular biology. This 5-week course will provide introductory tools in bioinformatics in six areas. This course will cover 5 weekly publication-based discussions and data analysis sessions that will take place in a three-hour weekly session, Fridays from 1-4 p.m. at The University of Texas MD Anderson Cancer Center, Smithville Campus. Each lecture period will start with a one-hour discussion of a primary bioinformatics paper from the literature, with student-led discussion, moderated by course co-organizers. The class will then work on computers to analyze some of the data and understand how figures were generated. Instructors will be faculty from the Department of Epigenetics & Molecular Carcinogenesis.
GS04 1081 (3 credits)
Fall 2021 - 7 weeks, hands-on modular course.
Developmental Biology is one of the fundamental modern biological disciplines. This course provides an in-depth examination of the basic cellular, molecular, and genetic mechanisms by which a fertilized egg transforms into an organism with fully differentiated and functioning tissues and organs. Topics covered will include cell-to-cell communication, embryo patterning, tissue morphogenesis, cell differentiation, progenitor cells, advantages and disadvantages of classical and genetic model organisms for analyzing development, postembryonic development and regeneration, and the profound implications of developmental biology for medicine. The course is divided into hands-on lab modules, utilizing primary model organisms to examine the basic principles of developmental biology and will discuss current debates and recent findings that have yet to be simplified for textbook presentation.
Introduction to Bioinformatics
GS01 1143 (3 credits)
This course is intended to be an introduction to concepts and methods in bioinformatics with a focus on analyzing data merging from high throughput experimental pipelines such as next-gen sequencing. Students will be exposed to algorithms and software tools involved in various aspects of data processing and biological interpretation. Though some prior programming experience is highly recommended, it is not a requirement.
Principles of Stem Cell Biology
GS04 1072 (2 credits)
To be announced
Stem cells, be they embryonic or somatic, play crucial roles in the development and functional maintenance of individual organ systems and complete organisms. As has already been well demonstrated for the blood-forming system through bone marrow transplantation, stem cells can be utilized clinically for treatment of genetic or acquired diseases. The next couple of decades will undoubtedly provide many more successful clinical applications of stem cells in regenerative medicine. Stem cells may also play critical roles themselves in the initiation and maintenance of certain diseases, such as cancer. This course will provide a present-day understanding of the precise definition, molecular characterization, and biological function of stem cells. Our focus will primarily be on fundamental issues regarding stem cells, and less on their wide range of potential future applications. Completion of this course will adequately prepare students to both identify and understand fundamental issues in current stem cell research, as well as to contribute themselves to advancing this field through research.