Vahid Serpooshan
Associate Professor
The University of Texas Health Science Center at Houston
McGovern Medical School
Department of Pediatrics
My research program focuses on developing advanced 3D bioprinting, biomaterials, and
stem cell–based platforms to model human development and disease and to engineer
next-generation regenerative therapies, with a particular emphasis on cardiovascular and
pediatric diseases. By integrating nano-biomaterials, induced pluripotent stem cells
(iPSCs), mechanobiology, and biofabrication, my lab creates patient-specific, highprecision
in vitro tissue models that enable both fundamental discovery and translational
innovation.
A central goal of my research is to understand how biophysical, biochemical, and cellular
microenvironments regulate tissue development, disease progression, and repair. Current
projects include 3D bioprinted cardiac and vascular tissues, organ- and disease-on-chip
platforms (e.g., congenital heart disease and liver disease models), imaging-visible and
smart biomaterials, and cell-based regenerative therapies. These systems are used to
study human development, inflammation, fibrosis, ferroptosis, and therapeutic responses
in ways not possible with conventional models.
Graduate students in my laboratory work on interdisciplinary projects that span bioink
design, stem cell di?erentiation, tissue fabrication, advanced imaging, and functional
tissue characterization. Through tutorials and dissertation research, trainees gain handson
experience in 3D bioprinting, iPSC culture and di?erentiation, biomaterials synthesis,
quantitative imaging, experimental design, and data analysis, while also developing strong
skills in scientific writing, collaboration, and translational thinking. My mentoring
philosophy emphasizes creativity, rigor, independence, and teamwork, preparing students
for careers in academia, industry, and biomedical innovation.
McGovern Medical School Faculty
Education & Training
PhD, McGill University, 2011