Description

Finding and applying a suitable in-vivo model to investigate and solve a research problem remains a common challenge for graduate students. The purpose of this course is to convey fundamental knowledge in mouse genetics to inform the validity and suitability of different mouse models to address a research question. The course goes deep into the fundamentals of mouse genetics, from cutting edge gene editing and sequencing technologies commonly used to generate genetically modified (GM) mice, to ethical and regulatory frameworks regulating the use of GM animals. The course covers all aspects of mouse genetics required to explore the appropriate use of mouse models and how to collect and interpret experimental results.  Audit is permitted for this course.