Rosalie Griffin
Assistant Professor
The University of Texas MD Anderson Cancer Center at Houston
Department of Epidemiology and Lymphoma Myeloma
Our group studies how inherited genetic variation, clonal hematopoiesis, and precancerous conditions shape the risk and progression of blood cancers. At the intersection of molecular epidemiology, computational genomics, and clinical oncology, we integrate germline and somatic genomic data with large-scale cohort, biobank, and clinical datasets to uncover early molecular events that increase cancer risk. Our goal is to translate these findings into tools for precision risk prediction and cancer prevention.
Students in the lab gain hands-on experience in bioinformatics, statistical genomics, and multi-omics data integration using R/python and high-performance computing. Example projects include developing computational phenotyping methods to identify precursor conditions in large cohorts, characterizing clonal growth trajectories in cancer precursors, and investigating how inherited and acquired genomic alterations jointly shape cancer risk and prognosis.
Supported by the National Cancer Institute and the Cancer Prevention and Research Institute of Texas, our program offers access to diverse population datasets and a collaborative research environment. We welcome motivated students interested in genetic epidemiology, cancer genomics, and computational biology who want to explore how studying inherited genetics and early molecular events in blood can inform strategies for cancer prevention and interception.
Education & Training
PhD, University of Utah, 2020