GS14 1021 Current Topics in Neurobiology of Disease
- Course Director(s): John Byrne
- Semester: Fall
- Frequency: Annually
- Credit Hours: 1
- Grading System: Pass/Fail
- Prerequisites: None
Description
This course is an integrated approach to neurological diseases, which includes background information as well the diagnosis, the treatment, and the biological mechanisms of the diseases under study. The topic for Fall 2025 is “Dementia Prevention and Research.” This course will investigate the complex biological, clinical, and societal dimensions of Alzheimer’s disease and related dementias. Through a series of lectures, students will explore the cellular foundations of network abnormalities, covering topics such as functional genomics, autophagy, and proteasome dysfunction, along with the roles of the microbiome, inflammation, and glial cells in neurodegeneration. The course also adopts a clinical perspective by exploring advanced neuroimaging techniques, emerging therapeutic interventions, and the impact of cerebrovascular health in vascular dementia. The curriculum concludes with a focus on caregiving and the behavioral and psychological symptoms associated of dementia.
This course is open to graduate students, medical students, residents, and postdoctoral fellows.