Description

Du, Guangwei.  Four semester hours. Spring, annually. Grading System: Letter Grade. Prerequisites: Background in biochemistry and cell biology; Consent of instructor.

This course provides a detailed exploration of the molecular basis of cell signaling with emphasis on recent developments, structure-function, and quantitation.  The course will include both the regulation of second messenger systems (GPCRs, G proteins, cAMP, IP3 and lipid), ion channels, growth factor-regulated tyrosine kinases, small G proteins (ras, GEFs, Gaps), kinase/phosphatase pathways, steroid hormones/transcription, and the modeling of these systems.