Description

Lin, Ruitao. Three semester hours. Fall, even years. Grading System: Letter Grade. Prerequisite: Prior courses in probability and statistics, permission of the instructor.  Cross-listed course at Rice STAT 630.

This course will provide an overview of methods for the design and analysis of clinical trials. Topics will include fundamental principles and commonly used designs for phases I, II and III trials. Advanced topics will include flaws with many conventional methods, hybrid designs, dealing with multiple outcomes, bias correction, precision medicine, and Bayesian methods.