The University of Texas MD Anderson Cancer Center
Department of Gynecologic Oncology and Reproductive Medicine
My laboratory is interested in deciphering the molecular pathogenesis of ovarian cancer with a translational goal to identify potential prognostic biomarkers and therapeutic targets for individualized therapy. His current research focus is on rare ovarian cancer such as low-grade serous carcinoma and ovarian clear cell carcinoma.
- To understand the molecular pathogenesis in low-grade serous ovarian cancer and develop novel therapeutics.
- To decipher the molecular mechanisms of chemoresistance in ovarian cancer.
- To identify synthetic lethal genes in ovarian cancer cells.
- To develop therapeutics for ovarian clear cell carcinomas.
- To characterize a novel mouse model of leiomyoma.
Depending on the student’s interests, a tutorial in my laboratory would provide experience with high-throughput gene expression profiling and genotyping analysis with Affymetrix GeneChips, laser captured microdissection of tumor tissues, real-time quantitative PCR, basic cloning methods, bioinformatics, next sequencing analysis with Ion Torrent PGM, methylation analysis and the functional characterization of newly identified genes.
Education & Training
Ph.D. - The Chinese University of Hong Kong - 1990