Enzhuo (Michelle) Quan
MDA FCT8.6050 (Unit 1420)
The University of Texas MD Anderson Cancer Center
Department of Radiation Physics
My current research is mainly focused in the following areas. 1) Automation and quality control of treatment planning using 3D, IMRT and VMAT. Potential projects in this area include the analysis of target coverage and critical structure dose metrics for cervical, thoracic, and lumbar spine stereotactic radiation therapy treatment plans with one-, two-, and three-vertebral level involvement; development of standard planning structures and planning objectives for IMRT/VMAT plan optimization in RayStation for spine stereotactic radiosurgery; development of standard planning structures and planning objectives for VMAT plan optimization in RayStation for LINAC-based brain radiosurgery, etc. 2) Analysis of uncertainties in Spine stereotactic radiosurgery (SSRS) and development of strategies to account for uncertainties. Potential projects in this area include the analysis of the effect of spinal cord motion during MRI, MRI-CT registration in-accuracy, target and critical organ contouring in-accuracy, etc, in the delivered dose in SSRS, and the comparison of different image guidance strategies, including CBCT, ExacTrac, and ExacTrac Dynamic, in reducing the setup uncertainties of SSRS. 3) Optimization of target margin for frameless Gamma knife radiosurgery. 4) Pediatric radiation therapy. Potential projects include the immobilization techniques for pediatric patients and the application of the Optune Tumor Treating Field for pediatric patients with brain tumor. 5) Eye plaques brachytherapy for Uveal Melanoma. A potential project is the dosimetric comparison between COMS and Eye Physics eye plaques with an optic nerve notch for various eye and tumor sizes.
Education & Training
PhD, North Carolina State University, 2009