The University of Texas MD Anderson Cancer Center
Department of Surgical Oncology
Our laboratory focuses on mechanisms of metastasis, tumor cell maintenance and therapeutic vulnerabilities in pancreatic cancer. Discovery programs in the lab largely involve the identification of genes and transcriptional regulatory elements that drive metastasis in human cancers and genetic mouse models of cancer. Our lab has robust patient-derived model systems and unfettered access to fresh human tumor to leverage for discovery and therapeutics using high-resolution sequencing techniques and bioinformatics approaches.
Students can expect to acquire skills in traditional cell-based techniques/molecular biology, CRISPR/Cas9 applications, generation of mouse models, and computational analysis of existing and ongoing tumor-sequencing data generated by our translational research program. Students may also gain experience in preclinical therapeutics and translational research involving IRB-approved patient biospecimens and therapeutic compounds, generating computational strategies to test and identify tumor sensitivity/resistance based on molecular profiling.
Education & Training
M.D. - University of North Carolina-Chapel Hill School of Medicine - 2005