The University of Texas MD Anderson Cancer Center
Department of Radiation Physics
Research projects in Dr. Mohan’s lab are related to the following topics in radiation oncology physics:
- Characterization of physical properties of positively charged particles, i.e., protons and heavier ions (deuterons, He, Li, Be, B, C, O);
- Understanding the biological effects of protons and heavier ions and the clinically relevant relative biological effect (RBE) modeling for particle therapy.
- Robustness evaluation and robust LET- and variable RBE-incorporated optimization of intensity- and energy-modulated particle therapy
- Beam configuration optimization
- Understanding and personalized modeling of radiation-induced immune system toxicity and the development of dosimetric approaches to prevent or mitigate it.
- Immune system stimulation with radiotherapy with protons and heavier ions
- Personalized biophysical modeling of treatment response using A/I techniques and the incorporation of personalized response models into treatment optimization and selection of optimum treatment modality and technique specific to a patient’s characteristics;
- Understanding the underlying physical, radiochemical and radiobiological mechanisms of ultra-high dose rate (FLASH) radiotherapy with electrons, protons and heavier ions
Dissertation topics for students enrolled in Ph.D. programs will be selected from these areas. Students will also receive guidance and training in research methods.
Education & Training
PhD, Duke University, 1969