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CCTS TL1

Predoctoral & Postdoctoral Training
in Clinical & Translational Sciences
at UTHealth and MD Anderson Cancer Center

In general, "translational" science can be classified into four categories: T1, T2, T3, T4.

T1 / T2 [translating to patients]: making & adapting laboratory discoveries for treatment of human disease

T3 / T4 [translating to community]: establishing, disseminating, & implementing best practices for clinic- and community-based interventions

Translational research is not unidirectional; it is a type of continuum.  Community observations can inspire laboratory experiments just as laboratory animal studies can influence clinical treatment and community prevention initiatives.  And, at every T level, information needs to be disseminated for implementation.

In this program:

Clinical Research involves direct human subject interaction.

Translational Research can:

  • improve human health by reducing incidence, morbidity, or mortality of disease
  • make discoveries in a research laboratory and/or preclinical study, which can be developed into human studies
  • enhance the adoption of best practices in the community; comparative effectiveness of prevention and treatment

[definitions modified from recommendations by the NCI Translational Working Group (2006) and the CTSA RFA-RM-10-020]

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Contact Us

Co-Directors

Joya Chandra, PhD
jchandra@mdanderson.org 

Jeffrey A. Frost, PhD 
Jeffrey.A.Frost@uth.tmc.edu 

Co-Investigators

Shervin Assassi, MD  
Shervin.Assassi@uth.tmc.edu

Robert C. Bast, MD
rbast@mdanderson.org 

Program Contact

Nicolle Patterson, MS 
Nicolle.L.Patterson@uth.tmc.edu