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Hope Northrup

Hope Northrup

Regular Member


[email protected]
MSB 3.142

The University of Texas Health Science Center at Houston
McGovern Medical School
Department of Pediatrics

Research in my laboratory focuses on two disorders: tuberous sclerosis complex (TSC) and spina bifida cystica. TSC is inherited in an autosomal dominant fashion with two known genes on chromosome 9q34.3 (TSC1) and on chromosome 16p13.3 (TSC2) for the TSC phenotype. Current work underway includes mutational analysis and functional studies of both genes. The spina bifida project is using a candidate gene approach to search for genetic associations.

A tutorial in my laboratory will expose the student to common molecular genetic techniques including subcloning, DNA sequencing, Southern blot analysis, single strand conformational polymorphic analysis, cell free transcription-translation, protein-protein interaction techniques, Western blotting and immunoprecipitation.


McGovern Medical School Faculty

Education & Training

M.D. - Medical University of South Carolina - 1983


Faculty Development