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George Calin

George Calin

Regular Member


MDA 3SCR4.3424 (Unit 1950)

The University of Texas MD Anderson Cancer Center
Departments of Experimental Therapeutics and Translational Molecular Pathology

My long term scientific career goal is to establish the roles of non-coding RNAs in human diseases. In order to accomplish this, I plan to continue and expand in the next few years my previous work in the following way:

  1. Identification of the Roles of microRNAs and Other Non-Coding RNAs in Cancer Predisposition
  2. Identification of Non-Coding RNAs Involved in Metastasis
  3. Identification of microRNAs and Other Non-Coding RNAs as Diagnostic and Prognostic Markers in Human Cancers microRNAs as the Oldest Hormones
  4. Development of New Therapeutic Strategies Involving microRNAs and Other Non-Coding RNAs

Students rotating in the Calin laboratory would learn:

  • Genomics techniques related to non-codingRNAs (such as cloning, identification of genomics alterations or sequence variations)
  • Expression studies (by Northern blottings, quantitative PCr or microarray technology)
  • Identification of clinical and prognostic correlations between the different molecular signatures that we will identify and the clinical parameters
  • Achieve skills in the standard techniques used for construction of viral vectors important for the initial studies of gene therapy with microRNAs


MDACC Faculty

Calin Lab

Education & Training

MD, Carol Davila University of Medicine and Pharmacy, 1992
PhD, Carol Davila University of Medicine and Pharmacy, 2000