The University of Texas MD Anderson Cancer Center
Department of Leukemia
Department of Genomic Medicine
The Abbas lab is interested in applying integrative, multi-omic computational tools to understand the intrinsic and extrinsic factors associated with leukemia resistance to chemo and immunotherapy therapy. We apply epigenomics and transcriptomic tools including RNA, T- and B-cell receptor, and chromatin accessibility such as ATAC on bulk and single cell level to identify the interactions of leukemic cells with their microenvironment. Further, we leverage our clinical data of leukemia of more than 2000 patients to identify clinical and genomic markers associated with response. Rotating students in my lab will have the opportunity to work on projects focusing on immune mechanisms of resistance from readily available sequenced data. Graduate students who join the lab will have the opportunity to lead at least 1 dry-lab project and collaborate with other students and postdocs. We will provide a nurturing environment to guide and mentor students throughout their training to navigate these different areas. We will encourage and support students to apply to awards, fellowships and attend conferences.
Education & Training
MD, American University of Beirut, 2014
PhD, MD Anderson UTHealth Graduate School, 2010