The University of Texas MD Anderson Cancer Center
Department of Radiation Oncology
The research in my laboratory is directed at characterizing breast cancer stem and progenitor cells in human tissues including primary breast cancer and metastatic pleural effusions as well as in breast cancer cell lines. In particular we are examining the role of the cells in radiation resistance, particularly mediated by stem cell survival pathways such as Wnt/beta-catenin.
Depending on the student’s interests, a tutorial in my laboratory would provide a knowledge base in stem cell biology, radiation biology and molecular biology. A tutorial would also provide experience with stem cell culture, primary human tissue culture, molecular biology techniques including retroviral transduction, flow cytometry, fluorescent microscopy.
- Inflammatory Breast Cancer: The Cytokinome of Post-Mastectomy Wound Fluid Augments Proliferation, Invasion, and Stem Cell Markers
- A multi-institutional prediction model to estimate the risk of recurrence and mortality after mastectomy for T1-2N1 breast cancer
- Immediate Breast Reconstruction in Inflammatory Breast Cancer: Are We There Yet?
- Adoption of Ultrahypofractionated Radiation Therapy in Patients With Breast Cancer
- Locoregional Management and Prognostic Factors in Breast Cancer With Ipsilateral Internal Mammary and Axillary Lymph Node Involvement
- Trends in Sentinel Lymph Node Biopsies in Patients With Inflammatory Breast Cancer in the US
- Comparative transcriptional analyses of preclinical models and patient samples reveal MYC and RELA driven expression patterns that define the molecular landscape of IBC
- Chemotherapy Triggers T Cells to Remodel the Extracellular Matrix and Promote Metastasis
- How should radiation be done for inflammatory breast cancer patients?-a narrative review of modern literature
- Why diagnosing inflammatory breast cancer is hard and how to overcome the challenges: a narrative review
- NDRG1 in Aggressive Breast Cancer Progression and Brain Metastasis
- Contemporary Outcomes After Multimodality Therapy in Patients With Breast Cancer Presenting With Ipsilateral Supraclavicular Node Involvement
- Outcomes After Breast Radiation Therapy in a Diverse Patient Cohort With a Germline BRCA1/2 Mutation
- Breast Radiation Therapy-Related Treatment Outcomes in Patients With or Without Germline Mutations on Multigene Panel Testing
- Genomically Guided Breast Radiation Therapy: A Review of the Current Data and Future Directions
Education & Training
M.D./Ph.D. - Thomas Jefferson University - 2000