The University of Texas MD Anderson Cancer Center
Department of Radiation Oncology
The research in my laboratory is directed at characterizing breast cancer stem and progenitor cells in human tissues including primary breast cancer and metastatic pleural effusions as well as in breast cancer cell lines. In particular we are examining the role of the cells in radiation resistance, particularly mediated by stem cell survival pathways such as Wnt/beta-catenin.
Depending on the student’s interests, a tutorial in my laboratory would provide a knowledge base in stem cell biology, radiation biology and molecular biology. A tutorial would also provide experience with stem cell culture, primary human tissue culture, molecular biology techniques including retroviral transduction, flow cytometry, fluorescent microscopy.
- Inclusion of premenopausal women in breast cancer clinical trials
- Reply to J. Widder
- ASO Visual Abstract: Long-Term Oncologic Outcomes in Patients with Inflammatory Breast Cancer with Supraclavicular Nodal Involvement
- ASO Visual Abstract: Lymphedema in Inflammatory Breast Cancer Patients Following Trimodal Treatment
- Lymphedema in Inflammatory Breast Cancer Patients Following Trimodal Treatment
- Long-term Oncologic Outcomes in Patients with Inflammatory Breast Cancer with Supraclavicular Nodal Involvement
- Prediction of breast cancer-related lymphedema by dermal backflow detected with near-infrared fluorescence lymphatic imaging
- Inflammatory Breast Cancer: The Cytokinome of Post-Mastectomy Wound Fluid Augments Proliferation, Invasion, and Stem Cell Markers
- A multi-institutional prediction model to estimate the risk of recurrence and mortality after mastectomy for T1-2N1 breast cancer
- Immediate Breast Reconstruction in Inflammatory Breast Cancer: Are We There Yet?
- Adoption of Ultrahypofractionated Radiation Therapy in Patients With Breast Cancer
- Locoregional Management and Prognostic Factors in Breast Cancer With Ipsilateral Internal Mammary and Axillary Lymph Node Involvement
- Trends in Sentinel Lymph Node Biopsies in Patients With Inflammatory Breast Cancer in the US
- Comparative transcriptional analyses of preclinical models and patient samples reveal MYC and RELA driven expression patterns that define the molecular landscape of IBC
- Chemotherapy Triggers T Cells to Remodel the Extracellular Matrix and Promote Metastasis
Education & Training
M.D./Ph.D. - Thomas Jefferson University - 2000