Wendy Woodward
Professor
The University of Texas MD Anderson Cancer Center
Department of Radiation Oncology
The research in my laboratory is directed at characterizing breast cancer stem and progenitor cells in human tissues including primary breast cancer and metastatic pleural effusions as well as in breast cancer cell lines. In particular we are examining the role of the cells in radiation resistance, particularly mediated by stem cell survival pathways such as Wnt/beta-catenin.
Depending on the student’s interests, a tutorial in my laboratory would provide a knowledge base in stem cell biology, radiation biology and molecular biology. A tutorial would also provide experience with stem cell culture, primary human tissue culture, molecular biology techniques including retroviral transduction, flow cytometry, fluorescent microscopy.
Publications
- The impact of breast radiotherapy on the tumor genome and immune ecosystem
- Inhibition of MCL-1 and MEK overcomes MEK inhibitor resistance in triple-negative and inflammatory breast cancers
- Development of a Multi-Institutional Dataset to Validate a Novel Inflammatory Breast Cancer Diagnostic Score
- Cholesterol efflux protein, ABCA1, supports anti-cancer functions of myeloid immune cells
- Deescalation Perils in Inflammatory Breast Cancer
- Genomic and transcriptomic analyses identify distinctive features of triple-negative inflammatory breast cancer
- Outcomes After Palliative Radiation Therapy in Patients With Symptomatic Locoregionally Advanced Breast Cancer
- Adding Metastasis-Directed Therapy to Standard-of-Care Systemic Therapy for Oligometastatic Breast Cancer (EXTEND): A Multicenter, Randomized Phase 2 Trial
- Immune checkpoint inhibitors for patients with metastatic triple-negative inflammatory breast cancer (INCORPORATE): An international cohort study
- PRECISE: Preoperative Radiation Therapy to Elicit Critical Immune Stimulating Effects-A Phase 2 Clinical Trial
- Self-Reported Management of Inflammatory Breast Cancer Among the American Society of Breast Surgeons Membership: Consensus and Opportunities
- In Vivo Simvastatin and Brain Radiation in a Model of HER2 + Inflammatory Breast Cancer Brain Metastasis
- Onabotulinum toxin injections for shoulder and chest wall muscle pain in breast cancer survivors: retrospective study - preliminary report
- Premastectomy Radiotherapy and Immediate Breast Reconstruction: A Randomized Clinical Trial
- Neoadjuvant radioimmunotherapy synergy in triple-negative breast cancer: Is microenvironment-guided patient selection on the horizon?
Education & Training
M.D./Ph.D. - Thomas Jefferson University - 2000