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Aloke Sarkar

Aloke Sarkar

Associate Member

Assistant Professor

713-792-8028713-792-8028
[email protected]
4SCR3.1049

The University of Texas MD Anderson Cancer Center at Houston
Department of Experimental Therapeutics

Mitochondrial damage has been associated with several diseases, including cancer. Dysfunctional mitochondria (DyM) are eliminated via a unique process called mitochondrial autophagy (mitophagy). Understanding mechanisms of exclusion of damaged mitochondria is therefore key for discerning therapeutic susceptibilities in cancer cells. Recently, we and others identified a novel non-nuclear role of the master DNA damage sensor protein Ataxia telangiectasia mutated (ATM) in regulating mitophagy in multiple cancer cell lines.

PubMed

MDACC

Education & Training

PhD - Jadavpur University - 1996